Guidelines for the recognition and management of mixed depression.

نویسندگان

  • Stephen M Stahl
  • Debbi A Morrissette
  • Gianni Faedda
  • Maurizio Fava
  • Joseph F Goldberg
  • Paul E Keck
  • Yena Lee
  • Gin Malhi
  • Ciro Marangoni
  • Susan L McElroy
  • Michael Ostacher
  • Joshua D Rosenblat
  • Eva Solé
  • Trisha Suppes
  • Minoru Takeshima
  • Michael E Thase
  • Eduard Vieta
  • Allan Young
  • Mark Zimmerman
  • Roger S McIntyre
چکیده

A significant minority of people presenting with a major depressive episode (MDE) experience co-occurring subsyndromal hypo/manic symptoms. As this presentation may have important prognostic and treatment implications, the DSM-5 codified a new nosological entity, the "mixed features specifier," referring to individuals meeting threshold criteria for an MDE and subthreshold symptoms of (hypo)mania or to individuals with syndromal mania and subthreshold depressive symptoms. The mixed features specifier adds to a growing list of monikers that have been put forward to describe phenotypes characterized by the admixture of depressive and hypomanic symptoms (e.g., mixed depression, depression with mixed features, or depressive mixed states [DMX]). Current treatment guidelines, regulatory approvals, as well the current evidentiary base provide insufficient decision support to practitioners who provide care to individuals presenting with an MDE with mixed features. In addition, all existing psychotropic agents evaluated in mixed patients have largely been confined to patient populations meeting the DSM-IV definition of "mixed states" wherein the co-occurrence of threshold-level mania and threshold-level MDE was required. Toward the aim of assisting clinicians providing care to adults with MDE and mixed features, we have assembled a panel of experts on mood disorders to develop these guidelines on the recognition and treatment of mixed depression, based on the few studies that have focused specifically on DMX as well as decades of cumulated clinical experience.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Design and Validation of Stress Management Training Program for First-Grade Female High School Teachers in Shahriar City

Introduction: The purpose of this study was to design a stress management training program and determine its effectiveness on the quality of work life, career engagement and professional ethics for high school teachers. Methodology: The research was done in a mixed method in two stages. The first stage was qualitative that training package was created and the second stage was quantitative, impl...

متن کامل

Assessing mental health literacy: What medical sciences students’ know about depression

  Background: Mental health literacy is an individual’s knowledge and belief about mental disorders which aid their recognition, management and prevention. The aim of this study was to investigate mental health literacy among students of Tehran University of Medical Sciences.   Methods : In this cross-sectional study, data were collected by the anonymous self-administered questionnaires and fin...

متن کامل

The Evaluation of Anxiety, Depression and Global Assessment of Functioning in Bipolar Patients at Manic and Mixed Episodes

Background and Aims: This research is carried out with the aim of comparing anxiety, depression and global assessment of functioning between two groups of bipolar patients at mixed and manic episodes. Methods: Using an analytical cross-sectional approach, a sample of 94 patients with mean age of 32 years old (Standard Deviation: 11.3), who had been categorically diagnosed with bipolar disorder ...

متن کامل

Attention Processing in Depressed Mood: Testing Defocused Attention Hypothesis

Depressed mood effects attention and its span. The present study aimed to compare the allocation of attention to relevant and irrelevant neutral stimuli in depressed and non-depressed participants. The studied populations include all the students from Azad university of Ahwaz and the undergraduate psychology students from Shahid Bahonar University of Kerman. After completion of Beck Depression ...

متن کامل

Association Between Facial Affect Recognition and Maladaptive Schema in People With Depressive Symptoms

Objective: Depressed patients harbor maladaptive schemas that distort social reality and impaired facial expression recognition. Thus, this study aims at identifying specific associations among depressive symptoms, early maladaptive schemas, and patterns of for recognizing facially expressed emotions. Methods: 100 subjects diagnosed with depressive symptoms were selected from a larger statisti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • CNS spectrums

دوره 22 2  شماره 

صفحات  -

تاریخ انتشار 2017